World Digestive Health Congress
University of Bordeaux
France
Professor of Bacteriology at University of Bordeaux, Faculty of Medicine
Laboratoire de Bactériologie, Hôpital Pellegrin, 33076 Bordeaux cedex,
France
Current
Position
· Consultant at
Hospital Pellegrin, Bordeaux
· Member of Team 2 of
INSERM Unit 1053
· Associate Scientific
Director of the French National Reference Centre for Campylobacters &
Helicobacters
Education
· 1972 Diploma of
Pharmacy, University of Bordeaux II
· 1980 Doctor of
Medicine, University of Bordeaux II
Post
Graduate Training
· 1977 Internship,
Centre Hospitalier de Bordeaux, Certificate of Bacteriology, University of
Bordeaux II
· 1981 Training in cell
biology research, Institute for Medical Research, Camden, New Jersey, USA
· 1984 Epidemiology
Intelligence Service Course, Center for Diseases Control, Atlanta, Georgia, USA
· 1985 Training in
Campylobacter research, Laboratory Centre for Diseases Control, Ottawa, Canada
· 1985 Diploma for
Study and Research in Human Biology, University René Descartes, Paris, France
· 1986 Diploma for
Authorisation to oversee research projects, University of Bordeaux II
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Academic
Appointments
· 1978 - 1982 Assistant
Professor of Bacteriology, University of Bordeaux II
· 1982 - 1990 Associate
Professor of Bacteriology, University of Bordeaux II
· 1990 - present
Professor of Bacteriology, University of Bordeaux II
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Other
Appointments
· 1993 - 2017
Scientific Director of the French National reference Centre for Campylobacters
and Helicobacters
· 2007 - 2015 Head of
the INSERM Unit 853 ‘Helicobacter infection, inflammation and cancer’
· 2006 - 2017 Head of
the Bacteriology Department of the Bordeaux University hospital
Awards
· Dr Honoris
Causa of Wroc?aw University, Poland 2005
· Grants have
been obtained from the World Health Organization, the Biomed I programme of the
European Commission (Eurohepygast 1994-1998), the French Ministry of Foreign
Affairs and a number of other institutions.
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Professional
Organisations
Member of:
· 1994 - present
Elected member of the European Gastro Club
· 1994 - present
Corresponding Fellow of the Infectious Diseases, Society of America
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Society
and Committee Memberships
· 1987 - present
Founding member and current secretary of the European Helicobacter &
Microbiota Study Group (EHMSG)
· 1990 - present
Subcommittee of the International Union of Microbiological Societies (IUMS) for
the taxonomy of Campylobacter and related organisms
· 1994 - 2010 Member of
the International Agency for Research on Cancer (IARC) committee which first
established the carcinogenic role of H. pylori infection
· 1994 - 2001 Elected
member of the European Gastro Club
· 1994-present
Corresponding Fellow of the Infectious Diseases Society of America (IDSA)
· 1997 Secretary of the
International Working Party which produced Guidelines for clinical trials
aiming at the eradication of Helicobacter pylori
· 2003 -
2007 Member of the INSERM committee for Infectious diseases (CSS1) and for
cancer (CT1)
· 2004 - 2011 Member of
the Scientific Committee of the United Gastroenterology Federation (UEGF)
· 2004 - 2008 Member of
the Scientific Committee of the University Victor Segalen Bordeaux 2
· 2006 - 2012 Member of
the Scientific Committee of the French Institute for Health Surveillance (InVS
· 2007 - 2018 Member of
the ‘Conseil National des Universités’ (CNU) section 45-01
· Member of the following societies:
· American
Gastroenterology Association (AGA),
· American Society of
Microbiology (ASM),
· European Society of
Clinical Microbiology and Infectious Diseases (ESCMID),
· Société Française de
Microbiologie (SFM),
· Société Nationale
Française de GastroEntérologie (SNFGE)
· Société de Pathologie
Infectieuse de Langue Française (SPILF)
· Co-organization
of the Maastricht conferences (I to V).of the EHMSG on the Management of H.
pylori infection
· Participation at the
following Consensus conferences:
Joint EPSGHAN and NASGHAN guidelines for H. pylori in children 2011 & 2017
EGILS (European Gastro-intestinal lymphoma study group) consensus report on
MALT lymphoma 2011
MAPS (Management of the Precancerous conditions and lesions of the Stomach)
guidelines 2012 & 2018
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Research
Interests
· H. pylori diagnosis
and epidemiology, selected aspects of pathogenicity, gastric cancer and
susceptibility to antimicrobial agents.
Books
published
· Gastroduodenal
pathology and Campylobacter pylori, Ed. Mégraud F., Lamouliatte H., Elsevier,
Amsterdam, 1989, 659 pages.
· Helicobacter pylori.
Method for clinical diagnosis and basic research. Ed. Lee A., Mégraud F.,
Saunders, London, 1995, 305 pages.
· Helicobacter pylori.
Ed. Mégraud F., Lamouliatte H., Elsevier, Paris, Vol 1, 380 pages (1996). Vol
2, 500 pages (1997) in French.
Co-editor of:
· The Year in
Helicobacter pylori (special issue of Current Opinion in Gastroenterology), Ed.
Malfertheiner P., Mégraud F., Michetti P., Price A. yearly from 1994 to 2001.
· The Year in
Helicobacter (special issue of the journal Helicobacter) Ed. Mégraud F.,
Malfertheiner P. yearly from 2002 to 2018.
Author of several chapters in different books published on Helicobacter pylori.
Publications
· PubMed: 462
publications
· Web of science: H
index 70; 22,434 citations
· 10 best
publications on Helicobacter :
- Mégraud F, Bonnet F, Garnier M, Lamouliatte H. Characterization of
"Campylobacter pyloridis" by culture, enzymatic profile, and protein
content. J Clin Microbiol. 1985;22(6):1007-10.
- Mégraud F, Brassens-Rabbé MP, Denis F, Belbouri A, Hoa DQ. Seroepidemiology
of Campylobacter pylori infection in various populations. J Clin Microbiol.
1989;27(8):1870-3.
- Monteiro L, Bonnemaison D, Vekris A, Petry KG, Bonnet J, Vidal R, Cabrita J,
Mégraud F. Complex polysaccharides as PCR inhibitors in feces: Helicobacter
pylori model. J Clin Microbiol. 1997;35(4):995-8
- Occhialini A, Urdaci M, Doucet-Populaire F, Bébéar CM, Lamouliatte H, Mégraud
F. Macrolide resistance in Helicobacter pylori: rapid detection of point
mutations and assays of macrolide binding to ribosomes. Antimicrob Agents
Chemother. 1997;41(12):2724-8
- Marais A, Mendz GL, Hazell SL, Mégraud F. Metabolism and genetics of
Helicobacter pylori: the genome era. Microbiol Mol Biol Rev. 1999;63(3):642-74.
- Avenaud P1, Marais A, Monteiro L, Le Bail B, Bioulac Sage P, Balabaud C,
Mégraud F. Detection of Helicobacter species in the liver of patients with and
without primary liver carcinoma. Cancer. 2000;89(7):1431-9.
- Broutet N, Tchamgoué S, Pereira E, Lamouliatte H, Salamon R, Mégraud F. Risk
factors for failure of Helicobacter pylori therapy--results of an individual
data analysis of 2751 patients. Aliment Pharmacol Ther. 2003;17(1):99-109.
- Oleastro M1, Ménard A, Santos A, Lamouliatte H, Monteiro L, Barthélémy P,
Mégraud F. Real-time PCR assay for rapid and accurate detection of point
mutations conferring resistance to clarithromycin in Helicobacter pylori. J
Clin Microbiol. 2003 ;41(1):397-402.
- Malfertheiner P, Bazzoli F, Delchier JC, Celiñski K, Giguère M, Rivière M,
Mégraud F; Pylera Study Group. Helicobacter pylori eradication with a capsule
containing bismuth subcitrate potassium, metronidazole, and tetracycline given
with omeprazole versus clarithromycin-based triple therapy: a randomised,
open-label, non-inferiority, phase 3 trial. Lancet. 2011;377:905-13.
- Mégraud F, Coenen S, Versporten A, Kist M, Lopez-Brea M, Hirschl AM, Andersen
LP, Goossens H, Glupczynski Y; Study Group participants. Helicobacter pylori
resistance to antibiotics in Europe and its relationship to antibiotic
consumption. Gut. 2013;62(1):34-42
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Editorial
Boards
· Assistant Editor of
Helicobacter
· Member of the
editorial board of the following journals:
- European Journal of Gastroenterology and Hepatology
- Clinical Microbiology and infection
- Minerva Gastroenterologica e Diabetologica
- Gut and liver
- Lancet Infectious Diseases (2001-2003)